Datasets (31)

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  • COLLECTIONS EURL-ECVAM
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EURL ECVAM Fish In Vitro Intrinsic Clearance Database

The Fish In Vitro Intrinsic Clearance database is an Excel™ workbook and includes fish in vitro intrinsic clearance rates derived with in-vitro methods using fish S9 fraction, hepatocytes, or microsomes. There are approximately 960 entries for 232 unique chemi...

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EURL ECVAM Fish In Vivo Biotransformation Database

The Fish In Vivo Biotransformation database is an Excel™ workbook and includes fish in vivo biotransformation data (whole body, biotransformation rate constant (kB) estimates). There are 1535 entries for 702 organic chemicals. The database has been compiled by...

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EURL ECVAM In Vivo Repeated Dose Toxicity Database

Repeated dose toxicity studies in animals form the basis of chemical safety evaluations. Many parameters can be measured and analysed to assess the potential of the test chemical to cause adverse effects in the test animals and predict potential adverse effect...

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Time and Concentration Responses of HepaRG

Chemical safety assessment requires information on both chronic and acute effects of toxicants. Traditionally, such information has been provided by a set of animal studies conducted over different durations, ranging from a single dose with observation of effe...

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EURL ECVAM library of reference chemicals

The EURL ECVAM library of reference chemicals is a catalogue of chemical lists that can be used to standardise, qualify, characterise or compare in vitro, in chimico and in silico methods and models. It contains chemical lists used in research and validation ...

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Survey Results on the validity of complex in vitro models

The survey constitued of 14 multiple answer questions, aimed to understand the stakholders' opinion on the current credibility and validity of complex in vitro models such as 3D spheroids, bioprinted tissues, bioreactor cultures and microphysiological systems ...

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Three Rs Education and Training Learning Scenarios

This dataset is a publicly accessible collection of learning scenarios which have been created by education professionals for use by educators who wish to teach topics under the umbrella of the Three Rs and alternative methods. The collection covers university...