COLLECTION

European Union Reference Laboratory for Alternatives to Animal Testing

Acronym: EURL-ECVAM

Description

The European Union is strongly committed to the Replacement, Reduction and Refinement of testing on animals (the 'Three Rs') as reflected in Directive 2010/63/EU on the protection of animals used for scientific purposes.

As mandated by the Directive, the Joint Research Centre (JRC) runs the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) which has the following duties: coordination and promotion of the development and use of alternative methods, including in the areas of basic and applied research and regulatory testing; coordination of the validation of alternative approaches at EU level; acting as a focal point for the exchange of information on the development of alternative approaches;

setting up, maintaining and managing public databases and information systems on alternative approaches and their state of development; and promotion of dialogue between legislators, regulators, and all relevant stakeholders, in particular, industry, biomedical scientists, consumer organisations and animal-welfare groups, with a view to the development, validation, regulatory acceptance, international recognition, and application of alternative approaches.

Contact

Email
clemens.wittwehr (at) ec.europa.eu

Science Areas

Health and consumer protection

Datasets (26)

DATASET | Last updated:
Time and Concentration Responses of HepaRG

Chemical safety assessment requires information on both chronic and acute effects of toxicants. Traditionally, such information has been provided by a set of animal studies conduct...

DATASET | Last updated:
EURL ECVAM library of reference chemicals

The EURL ECVAM library of reference chemicals is a catalogue of chemical lists that can be used to standardise, qualify, characterise or compare in vitro, in chimico and in silico ...

DATASET | Last updated:
Three Rs Education and Training Learning Scenarios

This dataset is a publicly accessible collection of learning scenarios which have been created by education professionals for use by educators who wish to teach topics under the um...

DATASET | Last updated:
JRC QSAR Model Database

The JRC QSAR Model Database is a historical archive providing information on the validity of Quantitative Structure-Activity Relationship (QSAR) models that were submitted to JRC's...

DATASET | Last updated:
EURL ECVAM Kinetic Parameters Dataset

The ECVAM KinParDB contains kinetic parameters on 100 chemicals (pharma, pesticides, industrial chemicals as well as environmental contaminants), each of which has been or still is...

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Three Rs Education and Training Courses and Resources

The purpose of the collection of these data undertaken between June and September in 2018 was to provide a snapshot overview of education and training courses and resources on the ...

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HTS DB of Nanomaterials on HepaRGs

The large amount of existing nanomaterials demands for rapid and reliable ways to test their potential toxicological effect on human health, preferably by means of relevant in vitr...

DATASET | Last updated:
Inventory of the 3Rs knowledge sources

In the context of the European Commission's Communication published in response to the European Citizens' Initiative "Stop Vivisection", Action 1 aimed to conduct an assessment of ...

DATASET | Last updated:
EURL ECVAM Rodent In Vitro Intrinsic Clearance Database

The rodent In Vitro Intrinsic Clearance database is an Excel™ workbook and includes rodent (mouse, rat) in vitro intrinsic clearance rates derived with in vitro methods using roden...

DATASET | Last updated:
EURL ECVAM Rodent In Vivo Biotransformation Database

The Rodent In Vivo Biotransformation database is an Excel™ workbook and includes rodent (mouse, rat) in vivo biotransformation data (clearance or elimination or half-life, and in m...

DATASET | Last updated:
EURL ECVAM Fish In Vitro Intrinsic Clearance Database

The Fish In Vitro Intrinsic Clearance database is an Excel™ workbook and includes fish in vitro intrinsic clearance rates derived with in-vitro methods using fish S9 fraction, hepa...

DATASET | Last updated:
EURL ECVAM Fish In Vivo Biotransformation Database

The Fish In Vivo Biotransformation database is an Excel™ workbook and includes fish in vivo biotransformation data (whole body, biotransformation rate constant (kB) estimates). The...

DATASET | Last updated:
ChemAgora

The ChemAgora web portal provides search capabilities to chemical data from resources available online, enabling users to cross-reference the substances they are working on with bo...

Additional information

Published by
European Commission, Joint Research Centre
Created date
2018-12-14
Modified date
2022-06-23
Landing page
https://ec.europa.eu/jrc/en/eurl/ecvam