DATASET

EURL ECVAM Review of non-animal models in biomedical research - Immuno-oncology

Collection: EURL-ECVAM : European Union Reference Laboratory for Alternatives to Animal Testing 

Description

It is widely recognised that immuno-oncology has revolutionised cancer treatment. Nevertheless there are still major hurdles in addressing several key medical questions. Among these, there is a lack of preclinical animal models capable of mimicking patient conditions and predicting responses to new therapies. Therefore, there is an ongoing need to develop more comprehensive, functional non-animal models. The European Commission’s Joint Research Centre (JRC) has carried out an extensive review of advanced non-animal models being used for basic and applied research into immuno-oncology. Researchers characterised and catalogued 542 models to make them more accessible for human relevant studies that avoid the use of animals. The review has been compiled by ALTER-N.A.M. consortium for EURL ECVAM (Joint Research Centre, Directorate for Health, Consumers and Reference Materials, Chemicals Safety and Alternative Methods Unit; contract number:JRC/IPR/2018/F.3/0035/OC)

Contact

Email
jrc-f3-enquiries (at) ec.europa.eu

Contributors

  • Adelaide Dura
  • Laura Gribaldo
  • Pierre Deceuninck

How to cite

Dura, Adelaide; Gribaldo, Laura; Deceuninck, Pierre (2021): EURL ECVAM Review of non-animal models in biomedical research - Immuno-oncology. European Commission, Joint Research Centre (JRC) [Dataset] PID: http://data.europa.eu/89h/352f7dfd-05cf-434b-a96a-7e270dc76573

Keywords

biomedical immuno-oncology non-animal

Data access

Review of advanced non-animal models for immuno-oncology
Download 
  • This dataset contains 542 non-animal models in the field of immuno-oncology, including information on their applications, biological relevance, diseases area, and level of throughput. This collection aims to cover all existing and in-development non-animal approaches to immuno-oncology, including

    in vitro, in silico and ex vivo approaches.

Publications

Publication
Advanced Non-animal Models in Biomedical Research — Immuno-oncology — Executive Summary
Gribaldo, L; Dura, A; Whelan M, Advanced Non-animal Models in Biomedical Research — Immuno-oncology — Executive Summary
Publication
Advanced Non-animal Models in Biomedical Research — Immuno-oncology
Romania, P; Folgiero, V; Nic, M; Dibusz, K; Novotny, T; Busquet, F; Rossi, F; Straccia, M; Daskalopoulos, E P; Gribaldo, L, Advanced Non-animal Models in Biomedical Research — Immuno-oncology

Geographic areas

European Union

Temporal coverage

From date To date
2014-01-01 2019-03-31

Additional information

Published by
European Commission, Joint Research Centre
Created date
2021-07-27
Modified date
2021-08-11
Issued date
2021-07-27
Landing page
https://ec.europa.eu/jrc/en/eurl/ecvam/knowledge-sharing-3rs/life-science-research/immuno-oncology 
Language(s)
English
Data theme(s)
Science and technology
Update frequency
irregular
Identifier
http://data.europa.eu/89h/352f7dfd-05cf-434b-a96a-7e270dc76573
Popularity