It is widely recognised that immuno-oncology has revolutionised cancer treatment. Nevertheless there are still major hurdles in addressing several key medical questions. Among these, there is a lack of preclinical animal models capable of mimicking patient conditions and predicting responses to new therapies. Therefore, there is an ongoing need to develop more comprehensive, functional non-animal models.
The European Commission’s Joint Research Centre (JRC) has carried out an extensive review of advanced non-animal models being used for basic and applied research into immuno-oncology. Researchers characterised and catalogued 542 models to make them more accessible for human relevant studies that avoid the use of animals.
The review has been compiled by ALTER-N.A.M. consortium for EURL ECVAM (Joint Research Centre, Directorate for Health, Consumers and Reference Materials, Chemicals Safety and Alternative Methods Unit; contract number:JRC/IPR/2018/F.3/0035/OC)
European Commission, Joint Research Centre (2026): EURL ECVAM Review of non-animal models in biomedical research - Immuno-oncology. [Dataset] doi: 10.2905/JRC.EG1XH7G PID: http://data.europa.eu/89h/352f7dfd-05cf-434b-a96a-7e270dc76573
biomedicalimmuno-oncologynon-animal
This dataset contains 542 non-animal models in the field of immuno-oncology, including information on their applications, biological relevance, diseases area, and level of throughput. This collection aims to cover all existing and in-development non-animal approaches to immuno-oncology, including in vitro, in silico and ex vivo approaches.
| From date | To date |
|---|---|
| 2014-01-01 | 2019-03-31 |
