Description
It is widely recognised that immuno-oncology has revolutionised cancer treatment. Nevertheless there are still major hurdles in addressing several key medical questions. Among these, there is a lack of preclinical animal models capable of mimicking patient conditions and predicting responses to new therapies. Therefore, there is an ongoing need to develop more comprehensive, functional non-animal models. The European Commission’s Joint Research Centre (JRC) has carried out an extensive review of advanced non-animal models being used for basic and applied research into immuno-oncology. Researchers characterised and catalogued 542 models to make them more accessible for human relevant studies that avoid the use of animals. The review has been compiled by ALTER-N.A.M. consortium for EURL ECVAM (Joint Research Centre, Directorate for Health, Consumers and Reference Materials, Chemicals Safety and Alternative Methods Unit; contract number:JRC/IPR/2018/F.3/0035/OC)
Contact
Contributors
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- Adelaide Dura
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- Laura Gribaldo
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- Pierre Deceuninck
How to cite
Dura, Adelaide; Gribaldo, Laura; Deceuninck, Pierre (2021): EURL ECVAM Review of non-animal models in biomedical research - Immuno-oncology. European Commission, Joint Research Centre (JRC) [Dataset] PID: http://data.europa.eu/89h/352f7dfd-05cf-434b-a96a-7e270dc76573
Keywords
biomedical immuno-oncology non-animal
Data access
This dataset contains 542 non-animal models in the field of immuno-oncology, including information on their applications, biological relevance, diseases area, and level of throughput. This collection aims to cover all existing and in-development non-animal approaches to immuno-oncology, including
in vitro, in silico and ex vivo approaches.
Publications
Geographic areas
Temporal coverage
From date | To date |
---|---|
2014-01-01 | 2019-03-31 |
Additional information
- Published by
- European Commission, Joint Research Centre
- Created date
- 2021-07-27
- Modified date
- 2021-08-11
- Issued date
- 2021-07-27
- Landing page
- https://ec.europa.eu/jrc/en/eurl/ecvam/knowledge-sharing-3rs/life-science-research/immuno-oncology
- Language(s)
- English
- Data theme(s)
- Science and technology
- Update frequency
- irregular
- Identifier
- http://data.europa.eu/89h/352f7dfd-05cf-434b-a96a-7e270dc76573
- Popularity
-