DATASET

EURL ECVAM Review of non-animal models in biomedical research - Breast Cancer

Collection: EURL-ECVAM : European Union Reference Laboratory for Alternatives to Animal Testing 

Description

Breast cancer is the most common cancer among women in the European Union and worldwide. Preclinical breast cancer research currently relies on animal models, mostly rodents. However, animal models mimic limited aspects of human breast cancer. The European Commission’s Joint Research Centre (JRC) has carried out an extensive review of advanced non-animal models being used for basic and applied research into breast cancer. Researchers characterised and catalogued 935 models to make them more accessible for human relevant studies that avoid the use of animals. The review has been compiled by the ALTER-N.A.M. consortium for EURL ECVAM (Joint Research Centre, Directorate for Health, Consumers and Reference Materials, Chemicals Safety and Alternative Methods Unit; contract number:JRC/IPR/2018/F.3/0035/OC)

Contact

Email
jrc-f3-enquiries (at) ec.europa.eu

Contributors

  • Adelaide Dura
  • Laura Gribaldo
  • Pierre Deceuninck
  • Ivana Campia

How to cite

Dura, Adelaide; Gribaldo, Laura; Deceuninck, Pierre; Campia, Ivana (2020): EURL ECVAM Review of non-animal models in biomedical research - Breast Cancer. European Commission, Joint Research Centre (JRC) [Dataset] PID: http://data.europa.eu/89h/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38

Keywords

non-animal biomedical breast cancer

Data access

Review of advanced non-animal models for breast cancer
Download 
  • This dataset contains 935 non-animal models in the field of Breast Cancer, including information on their applications, biological relevance, diseases area, and level of throughput. This collection aims to cover all existing and in-development non-animal approaches to breast cancer modelling, including

    in vitro, in silico and ex vivo approaches.

Publications

Publication
Advanced Non-animal Models in Biomedical Research: Breast Cancer
Folgiero, V., Romania, P., Rossi, F., Caforio, M., Nic, M., Dibusz, K., Novotny, T., Busquet, F., Straccia, M. and Gribaldo, L., Advanced Non-animal Models in Biomedical Research: Breast Cancer, EUR 30334/1 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-24689-3 (online), 978-92-76-24690-9 (print), doi:10.2760/618741 (online), 10.2760/180550, JRC122309.
Publication
Advanced Non-animal Models in Biomedical Research: Breast Cancer: Executive Summary
Gribaldo, L., Dura, A., Straccia, M. and Whelan, M., Advanced Non-animal Models in Biomedical Research: Breast Cancer: Executive Summary, EUR 30334/1 EN, Publications Office of the European Union, Luxembourg, 2020, ISBN 978-92-76-24711-1 (online), 978-92-76-24710-4 (print), doi:10.2760/475307 (online), 10.2760/44977, JRC122309.

Geographic areas

European Union

Temporal coverage

From date To date
2014-01-01 2018-03-31

Additional information

Published by
European Commission, Joint Research Centre
Created date
2020-10-27
Modified date
2021-07-27
Issued date
2020-10-27
Landing page
https://ec.europa.eu/jrc/en/page/breast-cancer 
Data theme(s)
Science and technology
Update frequency
irregular
Identifier
http://data.europa.eu/89h/ffebe454-ed9a-47cf-8a33-8cf70c1b7d38
Popularity
29 Sep 2021: 1 visits