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The Fish In Vivo Biotransformation database is an Excel™ workbook and includes fish in vivo biotransformation data (whole body, biotransformation rate constant (kB) estimates)....
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The ECVAM KinParDB contains kinetic parameters on 100 chemicals (pharma, pesticides, industrial chemicals as well as environmental contaminants), each of which has been or still...
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The JRC QSAR Model Database is a historical archive providing information on the validity of Quantitative Structure-Activity Relationship (QSAR) models that were submitted to...
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DB-ALM dataset is a publicly accessible collection of alternative method summaries and protocols. DB-ALM focuses primarily on methods submitted to EURL ECVAM for validation, and...
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In the context of the European Commission's Communication published in response to the European Citizens' Initiative "Stop Vivisection", Action 1 aimed to conduct an assessment...
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The Rodent In Vivo Biotransformation database is an Excel™ workbook and includes rodent (mouse, rat) in vivo biotransformation data (clearance or elimination or half-life, and...
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This dataset is a publicly accessible collection of learning scenarios which have been created by education professionals for use by educators who wish to teach topics under the...
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Neurodegenerative diseases pose major challenges for societies with rapidly aging populations. Existing therapies are limited, and only treat the symptoms. Research employing...
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The supplementary materials of the Nanocomput report comprise: S1: Inventory of Quantitative Structure-Property Relationship (QSPR) and Quantitative Structure-Activity...
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The rodent In Vitro Intrinsic Clearance database is an Excel™ workbook and includes rodent (mouse, rat) in vitro intrinsic clearance rates derived with in vitro methods using...
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Breast cancer is the most common cancer among women in the European Union and worldwide. Preclinical breast cancer research currently relies on animal models, mostly rodents....
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The ChemAgora web portal provides search capabilities to chemical data from resources available online, enabling users to cross-reference the substances they are working on with...
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The EURL ECVAM Genotoxicity and Carcinogenicity Consolidated Database is a structured master database that compiles available genotoxicity and carcinogenicity information,...
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Respiratory diseases are a leading cause of death and disability worldwide. Research on human diseases relies extensively on animal models, however, effective new therapies for...
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The Fish In Vitro Intrinsic Clearance database is an Excel™ workbook and includes fish in vitro intrinsic clearance rates derived with in-vitro methods using fish S9 fraction,...
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The survey constitued of 14 multiple answer questions, aimed to understand the stakholders' opinion on the current credibility and validity of complex in vitro models such as 3D...
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The European Commission’s Joint Research Centre (JRC) runs the EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) which promotes regulatory acceptance of...
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The large amount of existing nanomaterials demands for rapid and reliable ways to test their potential toxicological effect on human health, preferably by means of relevant in...
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Collection of the current knowledge (in vitro and in vivo studies) related to the blood compatibility of nanomedicines and nanomaterials with a potential use in biomedical...
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In order to provide guidelines to design and perform a robust and reliable physical-chemical characterization of liposome-based nanomaterials, and to support method development...